MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription

Excessive fibrogenic response in the liver disrupts normal hepatic anatomy and function heralding such end-stage liver diseases as hepatocellular carcinoma and cirrhosis. Sinusoidal endothelial cells contribute to myofibroblast activation and liver fibrosis by undergoing endothelial-mesenchymal tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zilong, Chen, Baoyu, Dong, Wenhui, Kong, Ming, Fan, Zhiwen, Yu, Liming, Wu, Dongmei, Lu, Jun, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881349/
https://www.ncbi.nlm.nih.gov/pubmed/31776330
http://dx.doi.org/10.1038/s41419-019-2101-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881349/
https://www.ncbi.nlm.nih.gov/pubmed/31776330
http://dx.doi.org/10.1038/s41419-019-2101-4

Ejemplares similares