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MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription
Excessive fibrogenic response in the liver disrupts normal hepatic anatomy and function heralding such end-stage liver diseases as hepatocellular carcinoma and cirrhosis. Sinusoidal endothelial cells contribute to myofibroblast activation and liver fibrosis by undergoing endothelial-mesenchymal tran...
Autores principales: | Li, Zilong, Chen, Baoyu, Dong, Wenhui, Kong, Ming, Fan, Zhiwen, Yu, Liming, Wu, Dongmei, Lu, Jun, Xu, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881349/ https://www.ncbi.nlm.nih.gov/pubmed/31776330 http://dx.doi.org/10.1038/s41419-019-2101-4 |
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