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IL-23 induces regulatory T cell plasticity with implications for inflammatory skin diseases

Foxp3(+) regulatory T cells (Tregs) represent a major fraction of skin resident T cells. Although normally protective, Tregs have been shown to produce pro-inflammatory cytokines in human diseases, including psoriasis. A significant hurdle in the Treg field has been the identification, or developmen...

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Detalles Bibliográficos
Autores principales: Kannan, Arun K., Su, Zhi, Gauvin, Donna M., Paulsboe, Stephanie E., Duggan, Ryan, Lasko, Loren M., Honore, Prisca, Kort, Michael E., McGaraughty, Steve P., Scott, Victoria E., Gauld, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881359/
https://www.ncbi.nlm.nih.gov/pubmed/31776355
http://dx.doi.org/10.1038/s41598-019-53240-z