BATF3 is sufficient for the induction of Il9 expression and can compensate for BATF during Th9 cell differentiation

Th9 cells preferentially produce IL-9 and participate in allergic responses and asthma. Differentiation of Th9 cells is induced by IL-4 and TGF-β, and then the cells are amplified by OX40 signals. The transcription factors PU.1, IRF4, and BATF are required for Th9 differentiation. BATF3 is an AP-1 f...

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Detalles Bibliográficos
Autores principales: Lee, Woo Ho, Jang, Sung Woong, Kim, Hyeong Su, Kim, So Hee, Heo, Jung In, Kim, Ga Eul, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881360/
https://www.ncbi.nlm.nih.gov/pubmed/31776325
http://dx.doi.org/10.1038/s12276-019-0348-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881360/
https://www.ncbi.nlm.nih.gov/pubmed/31776325
http://dx.doi.org/10.1038/s12276-019-0348-6

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