G-CSFR antagonism reduces neutrophilic inflammation during pneumococcal and influenza respiratory infections without compromising clearance

Excessive neutrophilic inflammation can contribute to the pathogenesis of pneumonia. Whilst anti-inflammatory therapies such as corticosteroids are used to treat excessive inflammation, they do not selectively target neutrophils and may compromise antimicrobial or antiviral defences. In this study,...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Aloe, Christian, Wilson, Nick, Bozinovski, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881371/
https://www.ncbi.nlm.nih.gov/pubmed/31776393
http://dx.doi.org/10.1038/s41598-019-54053-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881371/
https://www.ncbi.nlm.nih.gov/pubmed/31776393
http://dx.doi.org/10.1038/s41598-019-54053-w

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