Syncytin 1 dependent horizontal transfer of marker genes from retrovirally transduced cells

Retroviral transduction is routinely used to generate cell lines expressing exogenous non-viral genes. Here, we show that human cells transduced to stably express GFP transfer GFP gene to non-transduced cells. This horizontal gene transfer was mediated by a fraction of extracellular membrane vesicle...

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Detalles Bibliográficos
Autores principales: Uygur, Berna, Melikov, Kamran, Arakelyan, Anush, Margolis, Leonid B., Chernomordik, Leonid V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881383/
https://www.ncbi.nlm.nih.gov/pubmed/31776415
http://dx.doi.org/10.1038/s41598-019-54178-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881383/
https://www.ncbi.nlm.nih.gov/pubmed/31776415
http://dx.doi.org/10.1038/s41598-019-54178-y

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