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Syncytin 1 dependent horizontal transfer of marker genes from retrovirally transduced cells

Retroviral transduction is routinely used to generate cell lines expressing exogenous non-viral genes. Here, we show that human cells transduced to stably express GFP transfer GFP gene to non-transduced cells. This horizontal gene transfer was mediated by a fraction of extracellular membrane vesicle...

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Detalles Bibliográficos
Autores principales:	Uygur, Berna, Melikov, Kamran, Arakelyan, Anush, Margolis, Leonid B., Chernomordik, Leonid V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881383/ https://www.ncbi.nlm.nih.gov/pubmed/31776415 http://dx.doi.org/10.1038/s41598-019-54178-y

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