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A diarylamine derived from anthranilic acid inhibits ZIKV replication

Zika virus (ZIKV) is a mosquito-transmitted Flavivirus, originally identified in Uganda in 1947 and recently associated with a large outbreak in South America. Despite extensive efforts there are currently no approved antiviral compounds for treatment of ZIKV infection. Here we describe the antivira...

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Detalles Bibliográficos
Autores principales: Silva, Suely, Shimizu, Jacqueline Farinha, Oliveira, Débora Moraes de, Assis, Leticia Ribeiro de, Bittar, Cintia, Mottin, Melina, Sousa, Bruna Katiele de Paula, Mesquita, Nathalya Cristina de Moraes Roso, Regasini, Luis Octávio, Rahal, Paula, Oliva, Glaucius, Perryman, Alexander Luke, Ekins, Sean, Andrade, Carolina Horta, Goulart, Luiz Ricardo, Sabino-Silva, Robinson, Merits, Andres, Harris, Mark, Jardim, Ana Carolina Gomes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881388/
https://www.ncbi.nlm.nih.gov/pubmed/31776405
http://dx.doi.org/10.1038/s41598-019-54169-z