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A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus

Specific communication between gene promoters and enhancers is critical for accurate regulation of gene expression. However, it remains unclear how specific interactions between multiple regulatory elements contained within a single chromatin domain are coordinated. Recent technological advances whi...

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Detalles Bibliográficos
Autores principales: Oudelaar, A. Marieke, Harrold, Caroline L., Hanssen, Lars L. P., Telenius, Jelena M., Higgs, Douglas R., Hughes, Jim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881440/
https://www.ncbi.nlm.nih.gov/pubmed/31776347
http://dx.doi.org/10.1038/s41467-019-13404-x