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Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome

BACKGROUND: Fecal metabolites are associated with gut visceral sensitivity, mucosal immune function and intestinal barrier function, all of which have critical roles in the pathogenesis of irritable bowel syndrome (IBS). However, the metabolic profile and pathophysiology of IBS are still unclear. We...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Xue, Zhang, Yu, Qin, Geng, Li, Kai-Min, Wei, Wei, Li, Su-Yun, Yao, Shu-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881512/
https://www.ncbi.nlm.nih.gov/pubmed/31798278
http://dx.doi.org/10.3748/wjg.v25.i43.6416