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E and prM proteins of genotype V Japanese encephalitis virus are required for its increased virulence in mice

We previously showed that the Japanese encephalitis virus (JEV) genotype V (GV) strain Muar exhibits significantly higher virulence in mice than the genotype I (GI) JEV strain Mie/41/2002. In this study, we attempted to identify the region responsible for the increased virulence of GV JEV using reco...

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Detalles Bibliográficos
Autores principales: Tajima, Shigeru, Shibasaki, Ken-ichi, Taniguchi, Satoshi, Nakayama, Eri, Maeki, Takahiro, Lim, Chang-Kweng, Saijo, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881638/
https://www.ncbi.nlm.nih.gov/pubmed/31799464
http://dx.doi.org/10.1016/j.heliyon.2019.e02882