2D (2 Dimensional) TEQR design for Determining the optimal Dose for safety and efficacy

Designs, such as the Eff-Tox, OBD (optimal biological dose), STEIN (simple efficacy toxicity interval), and TEPI (toxicity efficacy probability interval) designs, have been proposed to determine the optimal dose of a new oncology drug using both efficacy and toxicity. The goal of these designs is to...

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Detalles Bibliográficos
Autores principales: Ananthakrishnan, Revathi, Green, Stephanie, Li, Daniel, LaValley, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881644/
https://www.ncbi.nlm.nih.gov/pubmed/31799471
http://dx.doi.org/10.1016/j.conctc.2019.100461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881644/
https://www.ncbi.nlm.nih.gov/pubmed/31799471
http://dx.doi.org/10.1016/j.conctc.2019.100461

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