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Glycerol not lactate is the major net carbon source for gluconeogenesis in mice during both short and prolonged fasting
OBJECTIVE: Fasting results in major metabolic changes including a switch from glycogenolysis to gluconeogenesis to maintain glucose homeostasis. However, the relationship between the length of fasting and the relative contribution of gluconeogenic substrates remains unclear. We investigated the rela...
Autores principales: | Wang, Yujue, Kwon, Hyokjoon, Su, Xiaoyang, Wondisford, Fredric E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881678/ https://www.ncbi.nlm.nih.gov/pubmed/31918920 http://dx.doi.org/10.1016/j.molmet.2019.11.005 |
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