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Control of doxorubicin-induced, reactive oxygen-related apoptosis by glutathione peroxidase 1 in cardiac fibroblasts

Reactive oxygen formation plays a mechanistic role in the cardiotoxicity of doxorubicin, a chemotherapeutic agent that remains an important component of treatment programs for breast cancer and hematopoietic malignancies. To examine the role of doxorubicin-induced reactive oxygen species (ROS) in dr...

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Detalles Bibliográficos
Autores principales: Doroshow, James H., Esworthy, R. Steven, Chu, Fong-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881695/
https://www.ncbi.nlm.nih.gov/pubmed/31799454
http://dx.doi.org/10.1016/j.bbrep.2019.100709