Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in Saccharomyces cerevisiae

Ribosomal DNA (rDNA) recombination in budding yeast is regulated by multiple converging processes, including posttranslational modifications such as SUMOylation. In this study, we report that the absence of a SUMO E3 ligase, Siz2, results in increased unequal rDNA exchange. We show that Siz2 is enri...

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Detalles Bibliográficos
Autores principales: Abraham, Neethu Maria, Ramalingam, Kathirvel, Murthy, Saketh, Mishra, Krishnaveni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881720/
https://www.ncbi.nlm.nih.gov/pubmed/31776241
http://dx.doi.org/10.1128/mSphere.00713-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881720/
https://www.ncbi.nlm.nih.gov/pubmed/31776241
http://dx.doi.org/10.1128/mSphere.00713-19

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