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5-Fluoro-2′-deoxycytidine as a Probe for the Study of B/Z-DNA Transition by (19)F NMR Spectroscopy

[Image: see text] 5-Fluoro-2′-deoxycytidine was synthesized by treating 5-fluoro-2′-deoxyuridine with 2,4,6-trimethylphenol in the presence of 1-methylpyrrolidine and trifluoroacetic anhydride, followed by aminolysis. Among N-acetyl, pivaloyl, and benzoyl, N-acetyl was found to be suitable for the p...

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Detalles Bibliográficos
Autores principales: Solodinin, Andrei, Gautrais, Angeline, Ollivier, Samuel, Yan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881825/
https://www.ncbi.nlm.nih.gov/pubmed/31788603
http://dx.doi.org/10.1021/acsomega.9b02461