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Rapid and ultrasensitive digital PCR (dPCR) profiling of EGFRvIII in tumor cells and tissues

BACKGROUND: Amplification of the epidermal growth factor receptor (EGFR) gene is commonly found in glioblastoma (GBM). About 57% GBM overexpresses EGFR and are associated with tumor progression, poor prognosis, and shorter life expectancy. Molecular profiling of solid tumors usually takes several we...

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Detalles Bibliográficos
Autores principales: Saxena, Deeksha, Sheikh, Saad, Kao, Gary, Binder, Zev A, Alonso-Basanta, Michelle, O’Rourke, Donald M, Nasrallah, MacLean P, Dorsey, Jay F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881905/
https://www.ncbi.nlm.nih.gov/pubmed/31807732
http://dx.doi.org/10.1093/noajnl/vdz030