Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels

BACKGROUND: MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator of ECM remodelling and cell migration. These processes are modulated by endogenous MMP inhibitors, such as RECK, a GPI-anchored protein which has been shown to inhibit both...

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Detalles Bibliográficos
Autores principales: Willson, Jessica A., Bork, Bradley S., Muir, Carlie A., Damjanovski, Sashko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881977/
https://www.ncbi.nlm.nih.gov/pubmed/31799217
http://dx.doi.org/10.1186/s40709-019-0108-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881977/
https://www.ncbi.nlm.nih.gov/pubmed/31799217
http://dx.doi.org/10.1186/s40709-019-0108-8

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