Detection of 8-oxoguanine and apurinic/apyrimidinic sites using a fluorophore-labeled probe with cell-penetrating ability

BACKGROUND: Reactive oxygen species (ROS) produce different lesions in DNA by ROS-induced DNA damage. Detection and quantification of 8-oxo-7,8-dihydroguanine (8-oxoG) within cells are important for study. Human ribosomal protein S3 (hRpS3) has a high binding affinity to 8-oxoG. In this study, we de...

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Detalles Bibliográficos
Autores principales: Kang, Dong Min, Shin, Jong-Il, Kim, Ji Beom, Lee, Kyungho, Chung, Ji Hyung, Yang, Hye-Won, Kim, Kil-Nam, Han, Ye Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881995/
https://www.ncbi.nlm.nih.gov/pubmed/31775627
http://dx.doi.org/10.1186/s12860-019-0236-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881995/
https://www.ncbi.nlm.nih.gov/pubmed/31775627
http://dx.doi.org/10.1186/s12860-019-0236-x

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