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The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective

Patients with advanced gastric cancer usually have a poor prognosis and limited therapeutic options. Overcoming this challenge requires novel targets and effective drugs. The Hedgehog (Hh) signaling pathway plays a crucial role in the development of the gastrointestinal tract and maintenance of the...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Song, Shumei, Wang, Zhenning, Ajani, Jaffer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882007/
https://www.ncbi.nlm.nih.gov/pubmed/31775795
http://dx.doi.org/10.1186/s12964-019-0479-3