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The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus

BACKGROUND: Neuroinflammation is thought to contribute to psychiatric and neurological disorders such as major depression and Alzheimer’s disease (AD). N-6 polyunsaturated fatty acids (PUFA) and molecules derived from them, including linoleic acid- and arachidonic acid-derived lipid mediators, are k...

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Detalles Bibliográficos
Autores principales: Alashmali, Shoug M., Lin, Lin, Trépanier, Marc-Olivier, Cisbani, Giulia, Bazinet, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882015/
https://www.ncbi.nlm.nih.gov/pubmed/31775778
http://dx.doi.org/10.1186/s12974-019-1615-0