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True and false positive rates for different criteria of evaluating statistical evidence from clinical trials

BACKGROUND: Until recently a typical rule that has often been used for the endorsement of new medications by the Food and Drug Administration has been the existence of at least two statistically significant clinical trials favoring the new medication. This rule has consequences for the true positive...

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Detalles Bibliográficos
Autores principales: van Ravenzwaaij, Don, Ioannidis, John P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882054/
https://www.ncbi.nlm.nih.gov/pubmed/31775644
http://dx.doi.org/10.1186/s12874-019-0865-y