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Use of Mendelian Randomization to Examine Causal Inference in Osteoporosis

Epidemiological studies have identified many risk factors for osteoporosis, however it is unclear whether these observational associations reflect true causal effects, or the effects of latent confounding or reverse causality. Mendelian randomization (MR) enables causal relationships to be evaluated...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Frysz, Monika, Kemp, John P., Evans, David M., Davey Smith, George, Tobias, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882110/
https://www.ncbi.nlm.nih.gov/pubmed/31824424
http://dx.doi.org/10.3389/fendo.2019.00807