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Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice
PURPOSE: Spinal cord injury (SCI) often results in significant and catastrophic dysfunction and disability and imposes a huge economic burden on society. This study aimed to determine whether progranulin (PGRN) plays a role in the progressive damage following SCI and evaluate the potential for devel...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882111/ https://www.ncbi.nlm.nih.gov/pubmed/31775776 http://dx.doi.org/10.1186/s12974-019-1630-1 |