Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

[Image: see text] Histone deacetylase 11 (HDAC11) preferentially removes fatty acid residues from lysine side chains in a peptide or protein environment. Here, we report the development and validation of a continuous fluorescence-based activity assay using an internally quenched TNFα-derived peptide...

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Detalles Bibliográficos
Autores principales: Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882135/
https://www.ncbi.nlm.nih.gov/pubmed/31788622
http://dx.doi.org/10.1021/acsomega.9b02808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882135/
https://www.ncbi.nlm.nih.gov/pubmed/31788622
http://dx.doi.org/10.1021/acsomega.9b02808

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