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Identification and ranking of recurrent neo-epitopes in cancer

BACKGROUND: Immune escape is one of the hallmarks of cancer and several new treatment approaches attempt to modulate and restore the immune system’s capability to target cancer cells. At the heart of the immune recognition process lies antigen presentation from somatic mutations. These neo-epitopes...

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Detalles Bibliográficos
Autores principales: Blanc, Eric, Holtgrewe, Manuel, Dhamodaran, Arunraj, Messerschmidt, Clemens, Willimsky, Gerald, Blankenstein, Thomas, Beule, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882202/
https://www.ncbi.nlm.nih.gov/pubmed/31775766
http://dx.doi.org/10.1186/s12920-019-0611-7