Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

BACKGROUND: Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence. The current WHO guideline recommends excludi...

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Detalles Bibliográficos
Autores principales: Dahal, Prabin, Stepniewska, Kasia, Guerin, Philippe J., D’Alessandro, Umberto, Price, Ric N., Simpson, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882216/
https://www.ncbi.nlm.nih.gov/pubmed/31775647
http://dx.doi.org/10.1186/s12874-019-0856-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882216/
https://www.ncbi.nlm.nih.gov/pubmed/31775647
http://dx.doi.org/10.1186/s12874-019-0856-z

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