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Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
BACKGROUND: Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence. The current WHO guideline recommends excludi...
Autores principales: | Dahal, Prabin, Stepniewska, Kasia, Guerin, Philippe J., D’Alessandro, Umberto, Price, Ric N., Simpson, Julie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882216/ https://www.ncbi.nlm.nih.gov/pubmed/31775647 http://dx.doi.org/10.1186/s12874-019-0856-z |
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