Cargando…

Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is a major cause of CNS neurodegeneration and has no disease-altering therapies. It is commonly associated with a specific type of biomechanical disruption of the axon called traumatic axonal injury (TAI), which often leads to axonal and sometimes perikaryal...

Descripción completa

Detalles Bibliográficos
Autores principales: Welsbie, Derek S., Ziogas, Nikolaos K., Xu, Leyan, Kim, Byung-Jin, Ge, Yusong, Patel, Amit K., Ryu, Jiwon, Lehar, Mohamed, Alexandris, Athanasios S., Stewart, Nicholas, Zack, Donald J., Koliatsos, Vassilis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882250/
https://www.ncbi.nlm.nih.gov/pubmed/31775817
http://dx.doi.org/10.1186/s13024-019-0345-1