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Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury
BACKGROUND: Traumatic brain injury (TBI) is a major cause of CNS neurodegeneration and has no disease-altering therapies. It is commonly associated with a specific type of biomechanical disruption of the axon called traumatic axonal injury (TAI), which often leads to axonal and sometimes perikaryal...
Autores principales: | Welsbie, Derek S., Ziogas, Nikolaos K., Xu, Leyan, Kim, Byung-Jin, Ge, Yusong, Patel, Amit K., Ryu, Jiwon, Lehar, Mohamed, Alexandris, Athanasios S., Stewart, Nicholas, Zack, Donald J., Koliatsos, Vassilis E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882250/ https://www.ncbi.nlm.nih.gov/pubmed/31775817 http://dx.doi.org/10.1186/s13024-019-0345-1 |
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