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The landscape of tyrosine kinase inhibitors in sarcomas: looking beyond pazopanib

Introduction: Tyrosine kinases are key mediators of intracellular signaling cascades and aberrations in these proteins have been implicated in driving oncogenesis through the dysregulation of fundamental cellular processes including proliferation, migration, and apoptosis. As such, targeting these p...

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Detalles Bibliográficos
Autores principales: Wilding, Christopher P, Elms, Mark L, Judson, Ian, Tan, Aik-Choon, Jones, Robin L, Huang, Paul H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882314/
https://www.ncbi.nlm.nih.gov/pubmed/31665941
http://dx.doi.org/10.1080/14737140.2019.1686979