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The landscape of tyrosine kinase inhibitors in sarcomas: looking beyond pazopanib
Introduction: Tyrosine kinases are key mediators of intracellular signaling cascades and aberrations in these proteins have been implicated in driving oncogenesis through the dysregulation of fundamental cellular processes including proliferation, migration, and apoptosis. As such, targeting these p...
Autores principales: | Wilding, Christopher P, Elms, Mark L, Judson, Ian, Tan, Aik-Choon, Jones, Robin L, Huang, Paul H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882314/ https://www.ncbi.nlm.nih.gov/pubmed/31665941 http://dx.doi.org/10.1080/14737140.2019.1686979 |
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