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Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition

BACKGROUND: Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved version of the light-driven chloride pump halorhodopsin d...

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Detalles Bibliográficos
Autores principales: Zhang, Chuanqiang, Yang, Shang, Flossmann, Tom, Gao, Shiqiang, Witte, Otto W., Nagel, Georg, Holthoff, Knut, Kirmse, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882325/
https://www.ncbi.nlm.nih.gov/pubmed/31775747
http://dx.doi.org/10.1186/s12915-019-0717-6