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Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition
BACKGROUND: Optogenetic silencing techniques have expanded the causal understanding of the functions of diverse neuronal cell types in both the healthy and diseased brain. A widely used inhibitory optogenetic actuator is eNpHR3.0, an improved version of the light-driven chloride pump halorhodopsin d...
Autores principales: | Zhang, Chuanqiang, Yang, Shang, Flossmann, Tom, Gao, Shiqiang, Witte, Otto W., Nagel, Georg, Holthoff, Knut, Kirmse, Knut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882325/ https://www.ncbi.nlm.nih.gov/pubmed/31775747 http://dx.doi.org/10.1186/s12915-019-0717-6 |
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