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Multiplex malaria antigen detection by bead-based assay and molecular confirmation by PCR shows no evidence of Pfhrp2 and Pfhrp3 deletion in Haiti

BACKGROUND: The Plasmodium falciparum parasite is the only human malaria that produces the histidine-rich protein 2 and 3 (HRP2/3) antigens. Currently, HRP2/3 are widely used in malaria rapid diagnostic tests (RDTs), but several global reports have recently emerged showing genetic deletion of one or...

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Detalles Bibliográficos
Autores principales: Herman, Camelia, Huber, Curtis S., Jones, Sophie, Steinhardt, Laura, Plucinski, Mateusz M., Lemoine, Jean F., Chang, Michelle, Barnwell, John W., Udhayakumar, Venkatachalam, Rogier, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882344/
https://www.ncbi.nlm.nih.gov/pubmed/31775743
http://dx.doi.org/10.1186/s12936-019-3010-9