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Directed evolution of the PcaV allosteric transcription factor to generate a biosensor for aromatic aldehydes

BACKGROUND: Transcription factor-based biosensors are useful tools for the detection of metabolites and industrially valuable molecules, and present many potential applications in biotechnology and biomedicine. However, the most common approach to develop biosensors relies on employing a limited set...

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Detalles Bibliográficos
Autores principales: F. M. Machado, Leopoldo, Currin, Andrew, Dixon, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882365/
https://www.ncbi.nlm.nih.gov/pubmed/31798685
http://dx.doi.org/10.1186/s13036-019-0214-z