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Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle–mediated release of ezrin to inhibit tumour cell movement

Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found that CD82 and other tetraspanins contain chol...

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Detalles Bibliográficos
Autores principales: Huang, Chao, Hays, Franklin A., Tomasek, James J., Benyajati, Siribhinya, Zhang, Xin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882436/
https://www.ncbi.nlm.nih.gov/pubmed/31807237
http://dx.doi.org/10.1080/20013078.2019.1692417