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Enhanced Ex Vivo Generation of Erythroid Cells from Human Induced Pluripotent Stem Cells in a Simplified Cell Culture System with Low Cytokine Support

Red blood cell (RBC) differentiation from human induced pluripotent stem cells (hiPSCs) offers great potential for developmental studies and innovative therapies. However, ex vivo erythropoiesis from hiPSCs is currently limited by low efficiency and unphysiological conditions of common culture syste...

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Detalles Bibliográficos
Autores principales: Bernecker, Claudia, Ackermann, Mania, Lachmann, Nico, Rohrhofer, Lisa, Zaehres, Holm, Araúzo-Bravo, Marcos J., van den Akker, Emile, Schlenke, Peter, Dorn, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882453/
https://www.ncbi.nlm.nih.gov/pubmed/31595840
http://dx.doi.org/10.1089/scd.2019.0132