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Mechanisms of oral absorption improvement for insoluble drugs by the combination of phospholipid complex and SNEDDS
In the present study, a water insoluble drug named silybin was encapsulated into self-nanoemulsifying drug delivery system (SNEDDS) following the preparation of silybin–phospholipid complex (SB–PC), then several methods were carried out to characterize SB–PC–SNEDDS and elucidate its mechanisms to im...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882455/ https://www.ncbi.nlm.nih.gov/pubmed/31736393 http://dx.doi.org/10.1080/10717544.2019.1686086 |