Identifying novel sphingosine kinase 1 inhibitors as therapeutics against breast cancer

Sphingosine kinase 1 (SphK1) is a promising therapeutic target against several diseases including mammary cancer. The aim of present work is to identify a potent lead compound against breast cancer using ligand-based virtual screening, molecular docking, MD simulations, and the MMPBSA calculations....

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Detalles Bibliográficos
Autores principales: Khan, Faez Iqbal, Lai, Dakun, Anwer, Razique, Azim, Iffat, Khan, Mohd Kalim Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882459/
https://www.ncbi.nlm.nih.gov/pubmed/31752564
http://dx.doi.org/10.1080/14756366.2019.1692828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882459/
https://www.ncbi.nlm.nih.gov/pubmed/31752564
http://dx.doi.org/10.1080/14756366.2019.1692828

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