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Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3
Previous reports have validated the glycogen synthase kinase-3 (GSK-3) as a druggable target against the human protozoan parasite Leishmania. This prompted us to search for new leishmanicidal scaffolds as inhibitors of this enzyme from our in-house library of human GSK-3β inhibitors, as well as from...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882465/ https://www.ncbi.nlm.nih.gov/pubmed/31752556 http://dx.doi.org/10.1080/14756366.2019.1693704 |