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Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3

Previous reports have validated the glycogen synthase kinase-3 (GSK-3) as a druggable target against the human protozoan parasite Leishmania. This prompted us to search for new leishmanicidal scaffolds as inhibitors of this enzyme from our in-house library of human GSK-3β inhibitors, as well as from...

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Detalles Bibliográficos
Autores principales: Martínez de Iturrate, Paula, Sebastián-Pérez, Victor, Nácher-Vázquez, Montserrat, Tremper, Catherine S., Smirlis, Despina, Martín, Julio, Martínez, Ana, Campillo, Nuria E., Rivas, Luis, Gil, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882465/
https://www.ncbi.nlm.nih.gov/pubmed/31752556
http://dx.doi.org/10.1080/14756366.2019.1693704