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Enhancement of zaleplon oral bioavailability using optimized self-nano emulsifying drug delivery systems and its effect on sleep quality among a sample of psychiatric patients

The aim of this work is to develop self-nano emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of zaleplon (Zal) as a poorly water-soluble drug. Moreover, the bioavailability and the effect on the quality of sleep among a sample of psychiatric patients is to be assessed....

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Detalles Bibliográficos
Autores principales: Khalifa, Maha K. A., Salem, Hoda A., Shawky, Seham M., Eassa, Heba A., Elaidy, Asmaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882476/
https://www.ncbi.nlm.nih.gov/pubmed/31752566
http://dx.doi.org/10.1080/10717544.2019.1687613