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Curcumin alleviates diabetic nephropathy via inhibiting podocyte mesenchymal transdifferentiation and inducing autophagy in rats and MPC5 cells

Context: Curcumin could ameliorate diabetic nephropathy (DN), but the mechanism remains unclear. Objective: The efficacy of curcumin on epithelial-to-mesenchymal transition (EMT) of podocyte and autophagy in vivo and in vitro was explored. Materials and methods: Thirty male Sprague–Dawley rats were...

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Detalles Bibliográficos
Autores principales: Tu, Qiudi, Li, Yiwen, Jin, Juan, Jiang, Xinxin, Ren, Yan, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882478/
https://www.ncbi.nlm.nih.gov/pubmed/31741405
http://dx.doi.org/10.1080/13880209.2019.1688843