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Curcumin alleviates diabetic nephropathy via inhibiting podocyte mesenchymal transdifferentiation and inducing autophagy in rats and MPC5 cells
Context: Curcumin could ameliorate diabetic nephropathy (DN), but the mechanism remains unclear. Objective: The efficacy of curcumin on epithelial-to-mesenchymal transition (EMT) of podocyte and autophagy in vivo and in vitro was explored. Materials and methods: Thirty male Sprague–Dawley rats were...
Autores principales: | Tu, Qiudi, Li, Yiwen, Jin, Juan, Jiang, Xinxin, Ren, Yan, He, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882478/ https://www.ncbi.nlm.nih.gov/pubmed/31741405 http://dx.doi.org/10.1080/13880209.2019.1688843 |
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