Dual activity of PNGM-1 pinpoints the evolutionary origin of subclass B3 metallo-β-lactamases: a molecular and evolutionary study

Resistance to β-lactams is one of the most serious problems associated with Gram-negative infections. β-Lactamases are able to hydrolyze β-lactams such as cephalosporins and/or carbapenems. Evolutionary origin of metallo-β-lactamases (MBLs), conferring critical antibiotic resistance threats, remains...

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Detalles Bibliográficos
Autores principales: Lee, Jung Hun, Takahashi, Masayuki, Jeon, Jeong Ho, Kang, Lin-Woo, Seki, Mineaki, Park, Kwang Seung, Hong, Myoung-Ki, Park, Yoon Sik, Kim, Tae Yeong, Karim, Asad Mustafa, Lee, Jung-Hyun, Nashimoto, Masayuki, Lee, Sang Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882493/
https://www.ncbi.nlm.nih.gov/pubmed/31749408
http://dx.doi.org/10.1080/22221751.2019.1692638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882493/
https://www.ncbi.nlm.nih.gov/pubmed/31749408
http://dx.doi.org/10.1080/22221751.2019.1692638

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