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Spinal cord stimulation prevents paclitaxel-induced mechanical and cold hypersensitivity and modulates spinal gene expression in rats

INTRODUCTION: Paclitaxel-induced peripheral neuropathy (PIPN) is a common dose-limiting side effect of this cancer treatment drug. Spinal cord stimulation (SCS) has demonstrated efficacy for attenuating some neuropathic pain conditions. OBJECTIVE: We aim to examine the inhibitory effect of SCS on th...

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Detalles Bibliográficos
Autores principales: Sivanesan, Eellan, Stephens, Kimberly E., Huang, Qian, Chen, Zhiyong, Ford, Neil C., Duan, Wanru, He, Shao-Qui, Gao, Xinyan, Linderoth, Bengt, Raja, Srinivasa N., Guan, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882571/
https://www.ncbi.nlm.nih.gov/pubmed/31875188
http://dx.doi.org/10.1097/PR9.0000000000000785