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A stroma-corrected ZEB1 transcriptional signature is inversely associated with antitumor immune activity in breast cancer

The epithelial-to-mesenchymal transition (EMT) is an essential developmental process which can be hijacked by cancer cells, leading to enhanced metastasis and chemoresistance in experimental models. Recent studies have linked gene expression of EMT-associated gene signatures to increased inflammator...

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Detalles Bibliográficos
Autores principales: Block, C. James, Dyson, Gregory, Campeanu, Ion John, Watza, Donovan, Ratnam, Manohar, Wu, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882801/
https://www.ncbi.nlm.nih.gov/pubmed/31780722
http://dx.doi.org/10.1038/s41598-019-54282-z