Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress

In this study, laryngeal tumor cells were killed through the production of excessive reactive oxygen species (ROS) and Ca(2+) influx by cisplatin (CISP). Nevertheless, a resistance was determined against CISP treatment in the tumor cells. We have investigated the stimulating role of curcumin (CURC)...

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Detalles Bibliográficos
Autores principales: Gökçe Kütük, Sinem, Gökçe, Gökçen, Kütük, Mustafa, Gürses Cila, Hacer Esra, Nazıroğlu, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882809/
https://www.ncbi.nlm.nih.gov/pubmed/31780732
http://dx.doi.org/10.1038/s41598-019-54284-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882809/
https://www.ncbi.nlm.nih.gov/pubmed/31780732
http://dx.doi.org/10.1038/s41598-019-54284-x

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