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Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress
In this study, laryngeal tumor cells were killed through the production of excessive reactive oxygen species (ROS) and Ca(2+) influx by cisplatin (CISP). Nevertheless, a resistance was determined against CISP treatment in the tumor cells. We have investigated the stimulating role of curcumin (CURC)...
Autores principales: | Gökçe Kütük, Sinem, Gökçe, Gökçen, Kütük, Mustafa, Gürses Cila, Hacer Esra, Nazıroğlu, Mustafa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882809/ https://www.ncbi.nlm.nih.gov/pubmed/31780732 http://dx.doi.org/10.1038/s41598-019-54284-x |
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