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In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis

Deficient bone vasculature is a key component in pathological conditions ranging from developmental skeletal abnormalities to impaired bone repair. Vascularisation is dependent upon vascular endothelial growth factor (VEGF), which drives both angiogenesis and osteogenesis. The aim of this study was...

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Detalles Bibliográficos
Autores principales: Rumney, Robin M. H., Lanham, Stuart A., Kanczler, Janos M., Kao, Alexander P., Thiagarajan, Lalitha, Dixon, James E., Tozzi, Gianluca, Oreffo, Richard O. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882814/
https://www.ncbi.nlm.nih.gov/pubmed/31780671
http://dx.doi.org/10.1038/s41598-019-53249-4